The Vanderbilt Mass Spectrometry Research Center is one of the most well-equipped academic research centers in the world, with more than 40 state-of-the-art mass spectrometers supporting cutting-edge proteomics, metabolomics, and imaging mass spectrometry workflows. Our comprehensive instrumentation suite enables high-resolution molecular characterization across scales, from single cells to whole tissues. Complementing these platforms, the center has a number of orthogonal technologies for multi-omics and spatial biology studies—including highly multiplexed immunofluorescence and advanced spatial transcriptomics systems—to empower integrated, multimodal analyses of complex biological systems.
Mass Spec
ABSciex Qtrap 6500 (2)
Agilent 6430 Triple Quad
Agilent 7700 ICP MS
Bruker timsTOF SCP Ultra
Bruker timsTOF HT (2)
Bruker timsMETABO
Bruker timsTOF Pro2
Bruker MALDI timsTOF Flex – MALDI-2
Bruker MALDI timsTOF Flex – Microgrid (2)
Bruker MALDI timsTOF Flex – Prototype
Bruker MALDI NeoFlex
Bruker MALDI RapiFlex Tissuetyper
Bruker MALDI UltraFlex (2)
Bruker MALDI 15T FT-ICR MS
Bruker nanoElute UPLC
Bruker nanoElute-2 UPLC (2)
Bruker nanoResolve UPLC
Dionex UltiMate 3000 nanoLC (3)
EvoSep One HPLC
HTX Imaging M5 Sprayer (2)
HTX Imaging M3 Sprayer (2)
HTX Imaging TM-Sprayer (2)
HTX Imaging Sublimate (2)
Thermo Orbitrap Fusion Tribrid MS
Thermo Orbitrap Exploris 240
Thermo Orbitrap Exploris 480
Thermo Velos Pro Orbitrap MS
Thermo QExactive HF Hybrid Quadrupole-Orbitrap
Thermo QExactive UHMR Orbitrap
Thermo LCQ Deca XP (LC/MS) ion trap
Thermo LTQ XL Orbitrap
Thermo TSQ Quantis triple quadrupole MS
Thermo Finnigan TSQ Quantum Ultra (2)
Thermo TSQ Vantage triple quadrupole MS
Thermo Electron DSQ GC/MS quadrupole MS
Thermo Electron Accela UPLC (2)
Thermo Easy-nLC (2)
Thermo Vanquish HPLC (4)
Waters Xevo G2-XS Q-TOF equipped with the LEAP HDX platform
Waters Xevo G2-XS QTOF
Waters Synapt Q-TOF MS
Waters Acquity UPLC systems (6)
Waters Acquity Premier
Waters Acquity M-Class UPLC
Microscopes
Akoya PhenoCycler-Fusion (2)
Leica SCN400 Slide Scanner
Nikon Eclipse 90i Brightfield Microscope
Olympus BX50 Brightfield Microscope
Zeiss Axioscan Z1 Fluorescence/Brightfield Slide Scanner
Zeiss Axio Observer 7 Inverted Fluorescence Microscope
Zeiss PALM MicroBeam LCM system
Transcriptomics
10x Xenium Analyzer
10x Visium/CytAssist
10x Chromium X
Illumina Miniseq
Nanostring/Bruker GeoMx Digital Spatial Profiler