{"id":82,"date":"2020-02-24T20:23:59","date_gmt":"2020-02-24T20:23:59","guid":{"rendered":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/?page_id=82"},"modified":"2022-07-18T16:26:51","modified_gmt":"2022-07-18T16:26:51","slug":"core-facilities","status":"publish","type":"page","link":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/core-facilities\/","title":{"rendered":"Core Facilities"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-271 aligncenter\" src=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-main\/medschool-dev\/wp-content\/uploads\/sites\/80\/2020\/03\/Cores.jpg\" alt=\"\" width=\"350\" height=\"320\" srcset=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-main\/medschool-dev\/wp-content\/uploads\/sites\/80\/2020\/03\/Cores.jpg 350w, https:\/\/cdn-dev.vanderbilt.edu\/t2-main\/medschool-dev\/wp-content\/uploads\/sites\/80\/2020\/03\/Cores-300x274.jpg 300w\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" \/><\/p>\n<p>Vanderbilt has a rich assortment of core facilities that provide access to techniques and equipment at the frontiers of biomedical research. Researchers have rapid and reliable access to a wide spectrum of support facilities that make doing chemical biology research at Vanderbilt a seamless, in-house operation. Synthesis of small molecules for the biologist, antibody production for use by chemists, rapid identification of structure using NMR and MS facilities, high level modeling of protein-drug interactions and final proof of concept using the HTS core are all part of the collaborative, interdisciplinary work environment at the VICB. The VICB operates:<\/p>\n<h4>High-Throughput Screening Core<\/h4>\n<p class=\"arial16\">The High-Throughput Screening Facility utilizes state-of-the art lab automation for sample storage, retrieval, and liquid handling and high-throughput plate readers, data management and analysis software to screen and interrogate chemical libraries.<\/p>\n<p>Libraries include 150,000 compounds selected to represent the chemical diversity of more than 1,000,000 MRSF accessible compounds and recombinant phage-displayed antibody libraries (~ 2.9 x 109 members) to identify reagents for use in research, diagnostic or therapeutic applications.\u00a0<a href=\"https:\/\/www.vanderbilt.edu\/hts\/\" target=\"_blank\" rel=\"noopener\">Visit the\u00a0High-Throughput Screening Core<\/a><\/p>\n<h4>Molecular Design and Synthesis Center<\/h4>\n<p class=\"arial16\"><span style=\"font-size: 1.2rem\">The practice of chemical synthesis allows access to known and\/or newly designed<br \/>\nchemical structures, including those with biological functions. The Vanderbilt Institute of<br \/>\nChemical Biology chemical synthesis core was founded in 2008 and renamed \u201cMolecular<br \/>\nDesign and Chemical Synthesis Center\u201d in 2021. Visit \u201cMolecular Design and Chemical<br \/>\nSynthesis Center. \u00a0<\/span><a href=\"https:\/\/medschool.dev.vanderbilt.edu\/syncore\/\" target=\"_blank\" rel=\"noopener\">Visit the Molecular Design and Chemical Synthesis Center<\/a><\/p>\n<p class=\"arial16orange\">\n","protected":false},"excerpt":{"rendered":"<p>Vanderbilt has a rich assortment of core facilities that provide access to techniques and equipment at the frontiers of biomedical research. Researchers have rapid and reliable access to a wide spectrum of support facilities that make doing chemical biology research at Vanderbilt a seamless, in-house operation. Synthesis of small molecules for the biologist, antibody production&#8230;<\/p>\n","protected":false},"author":177,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"jetpack_post_was_ever_published":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-82","page","type-page","status-publish","hentry"],"acf":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/PbG3q9-1k","_links":{"self":[{"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/pages\/82","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/users\/177"}],"replies":[{"embeddable":true,"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/comments?post=82"}],"version-history":[{"count":13,"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/pages\/82\/revisions"}],"predecessor-version":[{"id":1825,"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/pages\/82\/revisions\/1825"}],"wp:attachment":[{"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/media?parent=82"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medschool.dev.vanderbilt.edu\/vicb\/wp-json\/wp\/v2\/tags?post=82"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}