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Cryopreservation

Cryopreservation

Cryopreservation offers a reliable way to safeguard the integrity and long‑term viability of your genome‑edited mouse lines, ensuring they remain protected and ready for any future research needs. Selecting sperm or embryo cryopreservation for your mouse line depends on several key biological and project‑specific factors. Consider our cryopreservation services:

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Key Factors

Important considerations when choosing sperm or embryo cryopreservation:

FactorSpermEmbryo
Cost to FreezeLowMedium to High
Cost to RecoverMedium to HighLow
Time to FreezeLowMedium to High
Time to RecoverMediumLow
ReliabilityHighHigh
Genotype ProducedHeterozygousHeterozygous/Homozygous
AdvantagesOnly requires 2 malesCan be quickly rederived
LimitationsPups from IVF will be heterozygousRequires up to 10 males and females to maintain homozygous lines per cryopreservation event
Optimal UseStrains with single mutationsStrains with multiple mutations

Cryopreservation Benefits

When your research depends on unique, high‑value mouse models, cryopreservation gives you peace of mind and the freedom to focus on discovery instead of colony maintenance.

Why researchers choose cryopreservation:

  • Unmatched protection for irreplaceable lines
    Safeguard your strains against unforeseen events—from facility emergencies to breeding interruptions.

  • Guaranteed genetic integrity
    Lock in the exact genetics you rely on and eliminate the risk of drift over time.

  • Stronger biosecurity for your colonies
    Keep your models safe from pathogens, outbreaks, and other health-related disruptions.

  • Continuity you can count on
    Access your lines whenever you need them, even if live breeding slows or stops.

  • Smarter, simpler distribution
    Ship frozen embryos or sperm—reducing stress on animals and streamlining logistics.

  • Significant cost savings
    Lower housing, husbandry, and genotyping expenses.

  • Future‑ready research planning
    Archive lines now and bring them back exactly when projects demand them.

  • More efficient colony management
    Avoid overcrowding and maintain lean, purposeful colonies.