Publications

2024

Smith SC, Krystofiak E, Ogden KM, Mammalian orthoreovirus can exit cells in extracellular vesicles PLoS pathogens. 2024 Jan 11; 20 (1) e1011637
Ransom MA, Blatt AM, Pua HH, Sucre JMS, The emerging role of extracellular vesicles in bronchopulmonary dysplasia American journal of physiology. Lung cellular and molecular physiology. 2024 Mar 12; 326 (5) L517-L523
von Lersner AK, Fernandes F, Ozawa PMM, Jackson M, Masureel M, Ho H, Lima SM, Vagner T, Sung BH, Wehbe M, Franze K, Pua H, Wilson JT, Irish JM, Weaver AM, Di Vizio D, Zijlstra A, Multiparametric Single-Vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution ACS nano. 2024 Apr 05; 18 (15) 10464-10484
Chen HC, Wang J, Coffey RJ, Patton JG, Weaver AM, Shyr Y, Liu Q, EVPsort: An Atlas of Small ncRNA Profiling and Sorting in Extracellular Vesicles and Particles Journal of molecular biology. 2024 Apr 10; 168571
Maniya NH, Kumar S, Franklin JL, Higginbotham JN, Scott AM, Gan HK, Coffey RJ, Senapati S, Chang HC, An anion exchange membrane sensor detects EGFR and its activity state in plasma CD63 extracellular vesicles from patients with glioblastoma Communications biology. 2024 Jun 03; 7 (1) 677

2023

Tutanov OS, Glass SE, Coffey RJ, Emerging connections between GPI-anchored proteins and their extracellular carriers in colorectal cancer Extracellular vesicles and circulating nucleic acids. 2023 May 18; 4 (2) 195-217
Barman B, Ramirez M, Dawson TR, Liu Q, Weaver AM, Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP-A Proteomics. 2023 Nov 05; 24 (11) e2300099
Jimenez L, Stolzenbach V, Ozawa PMM, Ramirez-Solano M, Liu Q, Sage J, Weaver AM, Extracellular vesicles from non-neuroendocrine SCLC cells promote adhesion and survival of neuroendocrine SCLC cells Proteomics. 2023 Nov 05; 24 (11) e2300030
Anyika T, Hong I, Ndukaife JC, Mirror-Enhanced Plasmonic Nanoaperture for Ultrahigh Optical Force Generation with Minimal Heat Generation Nano letters. 2023 Nov 21; 23 (24) 11416-11423
Smith SC, Krystofiak E, Ogden KM, Mammalian orthoreovirus can exit cells in extracellular vesicles bioRxiv : the preprint server for biology. 2023 Aug 29;
Hong I, Hong C, Tutanov OS, Massick C, Castleberry M, Zhang Q, Jeppesen DK, Higginbotham JN, Franklin JL, Vickers K, Coffey RJ, Ndukaife JC, Anapole-Assisted Low-Power Optical Trapping of Nanoscale Extracellular Vesicles and Particles Nano letters. 2023 Aug 08; 23 (16) 7500-7507
Hong C, Ndukaife JC, Scalable trapping of single nanosized extracellular vesicles using plasmonics Nature communications. 2023 Aug 09; 14 (1) 4801
Jeppesen DK, Zhang Q, Franklin JL, Coffey RJ, Extracellular vesicles and nanoparticles: emerging complexities Trends in cell biology. 2023 Feb 01; 33 (8) 667-681
Barman B, Ramirez M, Dawson TR, Liu Q, Weaver AM, Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP-A bioRxiv : the preprint server for biology. 2023 Jul 19;
Dixson AC, Dawson TR, Di Vizio D, Weaver AM, Context-specific regulation of extracellular vesicle biogenesis and cargo selection Nature reviews. Molecular cell biology. 2023 Feb 10; 24 (7) 454-476
Wang J, Chen HC, Sheng Q, Dawson TR, Coffey RJ, Patton JG, Weaver AM, Shyr Y, Liu Q, Systematic Assessment of Small RNA Profiling in Human Extracellular Vesicles Cancers. 2023 Jun 30; 15 (13)
LaPlante EL, Stürchler A, Fullem R, Chen D, Starner AC, Esquivel E, Alsop E, Jackson AR, Ghiran I, Pereira G, Rozowsky J, Chang J, Gerstein MB, Alexander RP, Roth ME, Franklin JL, Coffey RJ, Raffai RL, Mansuy IM, Stavrakis S, deMello AJ, Laurent LC, Wang YT, Tsai CF, Liu T, Jones J, Van Keuren-Jensen K, Van Nostrand E, Mateescu B, Milosavljevic A, exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers Cell genomics. 2023 Apr 20; 3 (5) 100303
Cable J, Witwer KW, Coffey RJ, Milosavljevic A, von Lersner AK, Jimenez L, Pucci F, Barr MM, Dekker N, Barman B, Humphrys D, Williams J, de Palma M, Guo W, Bastos N, Hill AF, Levy E, Hantak MP, Crewe C, Aikawa E, Adamczyk AM, Zanotto TM, Ostrowski M, Arab T, Rabe DC, Sheikh A, da Silva DR, Jones JC, Okeoma C, Gaborski T, Zhang Q, Gololobova O, Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report Annals of the New York Academy of Sciences. 2023 Mar 18; 1523 (1) 24-37
Zhang Q, Jeppesen DK, Higginbotham JN, Franklin JL, Coffey RJ, Comprehensive isolation of extracellular vesicles and nanoparticles Nature protocols. 2023 Mar 13; 18 (5) 1462-1487
Dawson TR, Weaver AM, Niche tension controls exosome production Nature cell biology. 2023 Mar 25; 25 (3) 377-378
Ransom MA, Bunn KE, Negretti NM, Jetter CS, Bressman ZJ, Sucre JMS, Pua HH, Developmental trajectory of extracellular vesicle characteristics from the lungs of preterm infants American journal of physiology. Lung cellular and molecular physiology. 2023 Jan 31; 324 (3) L385-L392
Sung BH, Weaver AM, Visualization of Exosome Release and Uptake During Cell Migration Using the Live Imaging Reporter pHluorin_M153R-CD63 Methods in molecular biology (Clifton, N.J.). 2023 2608 83-96

2022

Schwager SC, Young KM, Hapach LA, Carlson CM, Mosier JA, McArdle TJ, Wang W, Schunk C, Jayathilake AL, Bates ME, Bordeleau F, Antonyak MA, Cerione RA, Reinhart-King CA, Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis eLife. 2022 Dec 07; 11
Zhang C, Huo X, Zhu Y, Higginbotham JN, Cao Z, Lu X, Franklin JL, Vickers KC, Coffey RJ, Senapati S, Wang C, Chang HC, Electrodeposited magnetic nanoporous membrane for high-yield and high-throughput immunocapture of extracellular vesicles and lipoproteins Communications biology. 2022 Dec 10; 5 (1) 1358
Salomon Carlos, Das Saumya, Erdbrügger Uta, Kalluri Raghu, Lim Kiang, Olefsky M, Rice E, Sahoo Susmita, Tao Andy, Vader Pieter, Wang Qun, Weaver M, Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement Endocr Rev. 2022 Apr 21;
Michell L, Allen M, Cavnar B, Contreras M, Yu Minshi, Semler M, Massick Clark, Raby A, Castleberry Mark, Ramirez A, Zhu Wanying, May-Zhang Linda, Ifrim Anca, Carr Jeffrey, Terry G, Schwendeman Anna, Davies S, Sheng Quanhu, Linton F, Vickers C, Elucidation of physico-chemical principles of high-density lipoprotein-small RNA binding interactions J Bill Chem.. 2022 Apr 18;
Barman Bahnisikha, Sung Bong Hwan, Krystofiak Evan, Ping Jie, Ramirez Marisol, Millis Bryan, Allen Ryan, Prasad Nripesh, Chetyrkin Sergei, Calcutt M Wade, Vickers Kasey, Patton G, Liu Qi, Weaver Alissa, VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites Developmental Cell. 2022 Apr 7;
Ochieng Josiah, Korolkova Y, Li Guoliang, Jin Renjie, Chen Zhenbang, Matusik J, Adunyah Samuel, Sakwe M, Ogunkua Olugbemiga, Fetuin-A Promotes 3-Dimensional Growth in LNCaP Prostate Cancer Cells by Sequestering Extracellular Vesicles to Their Surfaces to Act as Signaling Platforms International Journal of Molecular Sciences. Int J Mol Sci. 2022 Apr 5;

2021

Abner Jessica J, Franklin Jeffrey L, Clement Margaret A, Hinger Scott A, Allen Ryan M, Liu Xiao, Kellner Stefanie, Wu Junzhou, Karijolich John, Liu Qi, Vickers Kasey C, Dedon Peter, Weaver Alissa M, Coffey Robert J, Patton James G, Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m 6 A consensus sequences Heliyon. 2021 Dec 2;
Sanchez Greg Berumen, Bunn Kaitlyn E, Pua Heather H, Rafat Marjan, Extracellular vesicles: mediators of intercellular communication in tissue injury and disease 2021 Oct 16;
Nation Grant, Saffold Cherie, Pua H, Secret messengers: Extracellular RNA communication in the immune system 2021 Sep 20;
Sung Bong Hwan, Parent Carole, Weaver Alissa, Extracellular vesicles: Critical players during cell migration 2021 Apr 2;
Chanaday Natali, Nosyreva Elena, Shin Ok-Ho, Zhang Hua, Aklan Iltan, Atasoy Deniz, Bezprozvanny Ilya, Kavalali Ege, Presynaptic store-operated Ca 2+ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress 2021 Mar 4;
Vilcaes A Alejandro, Chanaday Natali L, Kavalali Ege T, Interneuronal exchange and functional integration of synaptobrevin via extracellular vesicles 2021 Jan 20;

2020

Benjamin John, Plosa Erin, Sucre Jennifer, van der Meer Riet, Dave Shivangi, Gutor Sergey, Nichols David, Gulleman Peter, Jetter Christopher, Han Wei, Xin Matthew, Dinella Peter, Catanzarite Ashley, Kook Seunghyi, Dolma Kalsang, Lal Charitharth, Gaggar Amit, Blalock J Edwin, Newcomb Dawn, Richmond Bradley, Kropski Jonathan, Young Lisa, Guttentag Susan, Blackwell Timothy, Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD 2020 Oct 27;
Altei Wanessa, Pachane Bianca, Dos Santos Patty, Ribeiro Lígia, Hwan Sung Bong, Weaver Alissa, Selistre-de-Araújo Heloisa, Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles 2020 Sep 29;
Hinger Scott, Abner Jessica, Franklin Jeffrey, Jeppesen Dennis, Coffey Robert, Patton James, Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells 2020 Sep 26;
Didiano Dominic, Abner Jessica, Hinger Scott, Flickinger Zachary, Kent Matthew, Clement Margaret, Balaiya Sankarathi, Liu Qi, Dai Xiaozhuan, Levine Edward, Patton James, Induction of a proliferative response in the zebrafish retina by injection of extracellular vesicles 2020 Sep 22;
Mariscal Javier, Vagner Tatyana, Kim Minhyung, Zhou Bo, Chin Andrew, Zandian Mandana, Freeman Michael, You Sungyong, Zijlstra Andries, Yang Wei, Di Vizio Dolores, Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles 2020 Sep 18;
Wong Sara, Hepowit Nathaniel, Port Sarah, Yau Richard, Peng Yutian, Azad Nadia, Habib Alim, Harpaz Nofar, Schuldiner Maya, Hughson Frederick, MacGurn Jason, Weisman Lois, Cargo Release from Myosin V Requires the Convergence of Parallel Pathways that Phosphorylate and Ubiquitylate the Cargo Adaptor 2020 Sep 11;
Korolkova Olga, Widatalla Sarrah, Williams Stephen, Whalen Diva, Beasley Heather, Ochieng Josiah, Grewal Thomas, Sakwe Amos, Diverse Roles of Annexin A6 in Triple-Negative Breast Cancer Diagnosis, Prognosis and EGFR-Targeted Therapies 2020 Aug 14;
Lim Aaron, Rathmell W Kimryn, Rathmell Jeffrey, The Tumor Microenvironment as a Metabolic Barrier to Effector T Cells and Immunotherapy Elife. 2020 May 5;
Sung Bong Hwan, von Lersner Ariana, Guerrero Jorge, Krystofiak Evan, Inman David, Pelletier Roxanne, Zijlstra Andries, Ponik Suzanne, Weaver Alissa, A Live Cell Reporter of Exosome Secretion and Uptake Reveals Pathfinding Behavior of Migrating Cells Nat Commun.. 2020 Apr 29; 11 (1)
Tumolo JM, Hepowit NL, Joshi SS, MacGurn JA, A Snf1-related nutrient-responsive kinase antagonizes endocytosis in yeast PLoS genetics. 2020 Mar 19; 16 (3) e1008677

2019

Weaver AM, Patton JG, Argonautes in Extracellular Vesicles: Artifact or Selected Cargo? Cancer research. 2019 Nov 29; 80 (3) 379-381
Zaborowski MP, Cheah PS, Zhang X, Bushko I, Lee K, Sammarco A, Zappulli V, Maas SLN, Allen RM, Rumde P, György B, Aufiero M, Schweiger MW, Lai CP, Weissleder R, Lee H, Vickers KC, Tannous BA, Breakefield XO, Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles Scientific reports. 2019 Nov 22; 9 (1) 17387
Postema MM, Grega-Larson NE, Meenderink LM, Tyska MJ, PACSIN2-dependent apical endocytosis regulates the morphology of epithelial microvilli Molecular biology of the cell. 2019 Aug 07; 30 (19) 2515-2526
Schwager SC, Bordeleau F, Zhang J, Antonyak MA, Cerione RA, Reinhart-King CA, Matrix stiffness regulates microvesicle-induced fibroblast activation American journal of physiology. Cell physiology. 2019 Apr 24; 317 (1) C82-C92
Jimenez L, Yu H, McKenzie AJ, Franklin JL, Patton JG, Liu Q, Weaver AM, Quantitative Proteomic Analysis of Small and Large Extracellular Vesicles (EVs) Reveals Enrichment of Adhesion Proteins in Small EVs Journal of proteome research. 2019 Jan 23; 18 (3) 947-959
Pua HH, Happ HC, Gray CJ, Mar DJ, Chiou NT, Hesse LE, Ansel KM, Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses Cell reports. 2019 Jan 22; 26 (4) 933-944.e4
Das S, , Ansel KM, Bitzer M, Breakefield XO, Charest A, Galas DJ, Gerstein MB, Gupta M, Milosavljevic A, McManus MT, Patel T, Raffai RL, Rozowsky J, Roth ME, Saugstad JA, Van Keuren-Jensen K, Weaver AM, Laurent LC, The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research Cell. 2019 Apr 4; 177 (2) 231-242
Jeppesen DK, Fenix AM, Franklin JL, Higginbotham JN, Zhang Q, Zimmerman LJ, Liebler DC, Ping J, Liu Q, Evans R, Fissell WH, Patton JG, Rome LH, Burnette DT, Coffey RJ, Reassessment of Exosome Composition Cell. 2019 Apr 4; 177 (2) 428-445.e18
Zhang Q, Higginbotham JN, Jeppesen DK, Yang YP, Li W, McKinley ET, Graves-Deal R, Ping J, Britain CM, Dorsett KA, Hartman CL, Ford DA, Allen RM, Vickers KC, Liu Q, Franklin JL, Bellis SL, Coffey RJ, Transfer of Functional Cargo in Exomeres Cell reports. 2019 Apr 04; 27 (3) 940-954.e6
Engevik AC, Kaji I, Postema MM, Faust JJ, Meyer AR, Williams JA, Fitz GN, Tyska MJ, Wilson JM, Goldenring JR, Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes The Journal of cell biology. 2019 Sep 27; 218 (11) 3647-3662
Sato S, Vasaikar S, Eskaros A, Kim Y, Lewis JS, Zhang B, Zijlstra A, Weaver AM, EPHB2 carried on small extracellular vesicles induces tumor angiogenesis via activation of ephrin reverse signaling JCI insight. 2019 Oct 29;

2018

Ochieng J, Nangami G, Sakwe A, Moye C, Alvarez J, Whalen D, Thomas P, Lammers P, Impact of Fetuin-A (AHSG) on Tumor Progression and Type 2 Diabetes International journal of molecular sciences. 2018 Jul 29; 19 (8)
Sato S, Weaver AM, Extracellular vesicles: important collaborators in cancer progression Essays in biochemistry. 2018 May 15; 62 (2) 149-163
Sung BH, Weaver AM, Directed migration: Cells navigate by extracellular vesicles The Journal of cell biology. 2018 Jul 05; 217 (8) 2613-2614
Rojas JD, Papadopoulou V, Czernuszewicz TJ, Rajamahendiran RM, Chytil A, Chiang YC, Chong DC, Bautch VL, Rathmell WK, Aylward S, Gessner RC, Dayton PA, Ultrasound Measurement of Vascular Density to Evaluate Response to Anti-Angiogenic Therapy in Renal Cell Carcinoma IEEE transactions on bio-medical engineering. 2018 Jul 27; 66 (3) 873-880
Vagner T, Spinelli C, Minciacchi VR, Balaj L, Zandian M, Conley A, Zijlstra A, Freeman MR, Demichelis F, De S, Posadas EM, Tanaka H, Di Vizio D, Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma Journal of extracellular vesicles. 2018 Aug 07; 7 (1) 1505403
Allen RM, Zhao S, Ramirez Solano MA, Zhu W, Michell DL, Wang Y, Shyr Y, Sethupathy P, Linton MF, Graf GA, Sheng Q, Vickers KC, Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins Journal of extracellular vesicles. 2018 Aug 13; 7 (1) 1506198
Reis-Sobreiro M, Chen JF, Novitskaya T, You S, Morley S, Steadman K, Gill NK, Eskaros A, Rotinen M, Chu CY, Chung LWK, Tanaka H, Yang W, Knudsen BS, Tseng HR, Rowat AC, Posadas EM, Zijlstra A, Di Vizio D, Freeman MR, Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential Cancer research. 2018 Aug 28; 78 (21) 6086-6097
Ochieng J, Nangami G, Sakwe A, Rana T, Ingram S, Goodwin JS, Moye C, Lammers P, Adunyah SE, Extracellular histones are the ligands for the uptake of exosomes and hydroxyapatite-nanoparticles by tumor cells via syndecan-4 FEBS letters. 2018 Sep 20; 592 (19) 3274-3285
Maacha S, Hong J, von Lersner A, Zijlstra A, Belkhiri A, AXL Mediates Esophageal Adenocarcinoma Cell Invasion through Regulation of Extracellular Acidification and Lysosome Trafficking Neoplasia (New York, N.Y.). 2018 Sep 03; 20 (10) 1008-1022
Hinger SA, Cha DJ, Franklin JL, Higginbotham JN, Dou Y, Ping J, Shu L, Prasad N, Levy S, Zhang B, Liu Q, Weaver AM, Coffey RJ, Patton JG, Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells Cell reports. 2018 Oct 16; 25 (3) 715-725.e4

2017

Petrova RS, Webb KF, Vaghefi E, Walker K, Schey KL, Donaldson PJ, Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cells American journal of physiology. Cell physiology. 2017 Nov 08; 314 (2) C191-C201

Unknown

Jimenez L, Barman B, Jung YJ, Cocozza L, Krystofiak E, Saffold C, Vickers KC, Wilson JT, Dawson TR, Weaver AM, Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations Journal of extracellular vesicles. Unknown 12 (11) e12366
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ, , Théry C, Witwer KW, Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches Journal of extracellular vesicles. Unknown 13 (2) e12404
Wang-Bishop L, Wehbe M, Shae D, James J, Hacker BC, Garland K, Chistov PP, Rafat M, Balko JM, Wilson JT, Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma Journal for immunotherapy of cancer. Unknown 8 (1)
Zijlstra A, Di Vizio D, Size matters in nanoscale communication Nature cell biology. Unknown 20 (3) 228-230