Course Requirements for the Ph.D. in Biochemistry

A total of 24 hours of didactic courses are required for the Ph.D. in Biochemistry. These didactic courses are comprised of three parts: (1) first year courses required for all entering students as part of the IGP or QCB programs (16 hours are usually completed tin the first two semesters, which may include elective hours), (2) those required by the Department of Biochemistry, and (3) those taken as electives (6 hours, required in addition to any elective hours completed as part of the 16 hours completed during the first two semesters).  With DGS approval, transfer credits may count toward the minimum 24 didactic credit hours at Vanderbilt required by the Graduate School.

Biochemistry Ph.D. students are expected to have a textbook-level knowledge of general biochemistry, such as would be represented by a classical undergraduate textbook on this subject (e.g. L. Stryer or Voet and Voet) prior to entering the Biochemistry graduate program. A student who did not take biochemistry as an undergraduate or who needs to brush up on this material should do so during their first two years of graduate study (prior to their qualifying exam) either through independent study or through elective course work.

The required courses in the Department of Biochemistry are:

  • Biochemistry 8327

    2 hours (Fall)

    Seminar/Scientific Communication

The Department of Biochemistry offers the following courses as electives:

  • Biochemistry 8300

    1 hour (Spring)

    Introduction to Structural Biology

  • Biochemistry 8301

    1 hour (Spring)

    Enzyme Kinetics & Mechanism

  • Biochemistry 8302

    3 hours (Fall)

    Advanced Biochemistry, Cell Biology and Genetics

  • Biochemistry 8303

    2 hours

    Biomolecular X-Ray Crystallography (Prerequisite BCHM 300)

  • Biochemistry 8323

    1-6 hours (Fall, Spring & Summer before prelims)

    Special Problems & Experimental Techniques. NOTE: The mentor of the student is the instructor for BCHM8323 courses. The mentor must provide a written description to the Graduate School of the student’s activities for these courses prior to registration. The Graduate Program Administrator will facilitate obtaining the approval from the Graduate School.

  • Biochemistry 8336

    Biochemical & Molecular Toxicology

    3 hours (Fall)

  • Biochemistry 8337

    Molecular Aspects of Cancer Research

    1 hour (Spring)

  • Biochemistry 8343

    Biomolecular NMR Spectroscopy

    3 hours (Fall)

  • Biochemistry 8349

    Graduate Seminar in Molecular Biophysics

    1 hour (Spring)

  • Biochemistry 8352

    Analytical Proteomics

    2 hours (Spring)

  • Biochemistry 7999

    Variable

    Research for M.S. Degree*

  • Biochemistry 8999

    Variable

    Research in lab before qualifying exam*

  • Biochemistry 9999

    Variable

    Research in lab after passing qual exam*

*Research project courses [Biochemistry 7999, 8999, and 9999] are not considered didactic courses.

The Graduate School requires 72 hours (didactic and research—minimum of 24 didactic–) for a Ph.D.

A typical curriculum for a Biochemistry Ph.D. follows:

Total CreditsDidactic Credits
YEAR 1 - IGP or QCB CORE COURSES AND ELECTIVES
1616
YEAR 1 - SUMMER SEMESTER
BCHM 8999 (old 379) – PhD Dissertation Research6
YEAR 2 - FALL SEMESTER
BCHM 8327 – Seminar/Scientific Communication22
Elective(s)3
BCHM 8999 – PhD Dissertation Research4
YEAR 2 - SPRING SEMESTER
Elective(s)33
BCHM 8999 (379) – PhD Dissertation Research6
YEAR 2 - SUMMER SEMESTER
BCHM 8999 (379) – PhD Dissertation Research6
TOTAL CREDITS AT END OF SECOND YEAR4624
Year 3 and 4 – BCHM 8999/9999 (Ph.D. Dissertation Research)26
TOTAL CREDITS NEEDED FOR GRADUATION7224

The exact timing of when the student completes the required hours BCHM 8999/9999 needed to reach the 72 hour total for the Ph.D. program is flexible.

In addition to the Graduate School requirement for an overall ‘B’ average, the Department of Biochemistry stipulates that students who obtain one ‘F’ or 2 ‘C’s in any courses, which include first year IGP/QCB courses, will not be permitted to continue. Exceptions to this rule will be permitted only by consent of the Biochemistry Graduate Education Advisory Committee. Any such exceptions will include probationary conditions.

 

Expectations of Graduate Student Full-time Effort
Graduate students in the Biochemistry graduate program receiving Vanderbilt University financial support or services must devote full-time effort to graduate study. Students cannot accept jobs for pay within or outside the University unless prior approval is given by their advisor, the Director of Graduate Studies, and the Dean for the Office of Biomedical Research Education and Training. Exceptions to this rule include part-time internships and activities that contribute to career development and that do not exceed the time commitment outlined by the National Institutes of Health, service as course associates at Vanderbilt, and occasional and temporary part-time pursuits (e.g. house sitting). Engagement in outside employment without obtaining approval may result in loss of financial aid, including stipend.

 

Student and Advisor Expectations and the Laboratory Compact
The primary goal of the laboratory rotation process is to provide a structured opportunity for students and principal investigators to find a mutual match. There is no ‘perfect’ rotation format that will provide a student and advisor a truly comprehensive sense of whether an optimal match was made. Context-specific stressors often arise well after the rotation period – and these unanticipated events can present as a significant challenge to the interpersonal relationship between advisor and trainee. These challenges often derive from or are exacerbated by an insufficient level of communication regarding the expectations of student and advisor with each other. To improve communication and avoid surprises, advisors that train graduate students of the Biochemistry Graduate Program are required to have a Laboratory Compact that they share with students upon their entry into their respective laboratory (or earlier). The intent of the laboratory compact is NOT to strictly standardize the expectations between students and advisors across the entire Biochemistry graduate program. Rather, the laboratory compact is intended to serve as a transparent communication tool that defines the ground rules specific for a given lab and its unique culture. It should outline the responsibilities of both the student and mentor. The laboratory compact is expected to include, but is not limited to, the following topics:

• Work hour and attendance expectations including vacation policy
• Expectations for how to be a good laboratory citizen
• Expectations for record keeping including laboratory notebooks and data archiving
• Expectations for scholarly development and training
• Expectations for participation in seminars, lab meetings, journal clubs, Biochemistry
department activities, and other events.
• Description of the manuscript preparation and publication process.
• Responsibilities of the mentor such as providing resources, advice, evaluation, etc…

The laboratory compact is a tool for both the mentor and student. It is an addendum to and not a substitute for regular communication, completion of IDPs, and other advising activities.