Research, News & Discoveries

Jun. 22, 2020, 8:00 AM by Leigh MacMillan Lennox-Gastaut syndrome is a severe early-onset seizure disorder that includes cognitive and behavioral abnormalities. Its pathophysiology is largely unknown.  Recent whole-exome sequencing in patients with Lennox-Gastaut syndrome identified a spontaneous mutation in the gene encoding a GABA-A receptor subunit implicated in other childhood epilepsies. … Read More

By Dana Meeks Ten outstanding faculty members from across the university have been selected for the 2020 cohort of Chancellor Faculty Fellows. This group is composed of highly accomplished, recently tenured faculty from a wide variety of disciplines and areas of expertise. “Investing in this remarkable group of… Read More

Jun. 18, 2020, 11:00 AM by Leigh MacMillan Cells missing the protein HMCES are hypersensitive to DNA-damaging agents that cause a common type of DNA lesion — an “abasic” site. But the agents also generate other types of lesions associated with mutations and cell lethality, making it unclear whether HMCES… Read More

Jun. 18, 2020, 10:30 AM by Bill Snyder Single-cell RNA sequencing is a powerful tool for identifying transcriptomic variations and developmental trajectories in cell types that determine the course of diseases like cancer, with the goal of eventually improving diagnosis and treatment. … Read More

Jun. 12, 2020, 10:00 AM   by Leigh MacMillan Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions. The findings, reported in the American Journal of Human Genetics,… Read More

by Ryan Underwood Jun. 16, 2020, 4:23 PM Vanderbilt University’s Warren Center for Neuroscience Drug Discovery has entered into an exclusive worldwide licensing and collaboration agreement with San Diego-based ACADIA Pharmaceuticals Inc., which will seek to develop and commercialize treatments for central… Read More

Dear Colleagues, I am delighted to announce that David Cortez, PhD, has been named Associate Director for Basic Science Research at Vanderbilt-Ingram Cancer Center.  Dave joined Vanderbilt University in 2002 and is the Richard Armstrong Professor of Biochemistry. He is an expert in the field of DNA damage response… Read More

by Marissa Shapiro Jun. 17, 2020, 9:43 AM Houra Merrikh, principal investigator in the department of biochemistry, has been named a finalist in the 2020 Blavatnik National Awards for Young Scientists, in the Life Sciences category. Merrikh was selected as one of… Read More

by Marissa Shapiro Jun. 12, 2020, 10:22 AM Craig Lindsley, the William K. Warren, Jr. Chair in Medicine and University Professor of biochemistry, chemistry and pharmacology, has been named interim Editor-in-Chief of ACS Pharmacology & Translational Science in addition to his current… Read More

Jun. 9, 2020, 12:36 PM By Bill Snyder Vanderbilt University and the global biopharmaceutical company AstraZeneca have signed a new agreement that will enable AstraZeneca to advance two coronavirus-neutralizing antibodies discovered by the Vanderbilt Vaccine Center (VVC) into clinical development as a potential combination therapy for the prevention and… Read More