VUSM Research

Vanderbilt University Medical Center researchers are inviting non-health care essential workers to participate in a new Centers for Disease Control and Prevention (CDC)-funded study to better understand how they continue to be impacted by COVID-19 and to guide efforts to keep them and their families safe as new variants emerge. Read More

Prevalence, Risk Factors, and Sequelae of Asymptomatic Clostridioides difficile Colonization in Children with Cystic Fibrosis. Reasoner SA, Fazili IF, Bernard R, Parnell JM, Sokolow AG, Thomsen KF, Edwards KM, Brown RF, Nicholson MR. J Cyst Fibros. 2022… Read More

Correlated depressive symptoms within seroconcordant, expectant partners living with HIV in Zambézia Province, Mozambique: a cross-sectional study. Sack DE, Matino A, Graves E, Emilio A, Shepherd BE, De Schacht C, Audet CM. AIDS Care. 2022 Dec 6:1-9. doi: 10.1080/09540121.2022.2151558. Read More

Surgeons introduce a nomogram to more accurately quantify risk of positive circumferential resection margins. Nomograms are commonly used in oncology for risk assessment and to predict a patient’s surgical outcomes and survival. However, colorectal cancer surgeons have lacked such a tool. Instead, they have relied on… Read More

T cells specific for α-myosin drive immunotherapy-related myocarditis. Axelrod ML, Meijers WC, Screever EM, Qin J, Carroll MG, Sun X, Tannous E, Zhang Y, Sugiura A, Taylor BC, Hanna A, Zhang S, Amancherla K, Tai W, Wright JJ, Wei SC,… Read More

Women with inherited mutations in breast cancer genes have lifetime varying breast cancer risks, ranging from high (e.g., 40% or more for BRCA1, BRCA2, PALB2) to moderate (e.g., 20% or higher for ATM, CHEK2) risk genes.  Per national practice guidelines, risk-reducing bilateral mastectomy is a consideration for patients with inherited… Read More

Clostridioides difficile (C. diff), labeled an urgent threat by federal health officials, is a bacterium that can be associated with severe gastrointestinal events and is frequently hospital-acquired.  While the incidence of C. diff infections increased from the 1990s to the early 2000s, studies looking at the rate of infections more… Read More

Single-Cell Identification of Melanoma Biomarkers in Circulating Tumor Cells Fankhauser R, Chang M, Garrison Z, Berryman R, Lucero OM, Fuiten A, DePatie N, Seifert H, Kulkarni RP. Cancers. 2022; 14(19):4921. https://doi.org/10.3390/cancers14194921 The current standard for investigating tumors is surgical… Read More

Impaired Dynamic Sarcoplasmic Reticulum Ca Buffering in Autosomal Dominant CPVT2. Wleklinski MJ, Kryshtal DO, Kim K, Parikh SS, Blackwell DJ, Marty I, Iyer VR, Knollmann BC. Circ Res. 2022 Sep 14:101161CIRCRESAHA121320661. doi: 10.1161/CIRCRESAHA.121.320661. Online ahead of print. Background:… Read More

The legacy left behind by the late William (Bill) Long, MD, goes far beyond his many years as a beloved Nashville pediatrician. He was a quintessential clinician-educator, always helping advance the mission of Vanderbilt’s Department of Pediatrics and Monroe Carell Jr. Children’s Hospital at Vanderbilt. The family of the longtime… Read More