VUSM Research

Nationwide analysis finds variants may confer more than elevated risk of kidney disease. A sweeping analysis published in JAMA Internal Medicine found people harboring apolipoprotein 1 (APOL1) gene variants were at increased risk of developing acute kidney injury (AKI) and dying following… Read More

Approximating Projections of Conformational Boltzmann Distributions with AlphaFold2 Predictions: Opportunities and Limitations. Brown BP, Stein RA, Meiler J, Mchaourab HS. J Chem Theory Comput. 2024 Jan 12. doi: 10.1021/acs.jctc.3c01081. Online ahead of print. Protein thermodynamics is intimately… Read More

Collegiate tennis players aren’t using enough sunscreen, a new survey finds. And collegiate golfers aren’t either.  As reported in Clinics in Dermatology, Georgina Sellyn, MA, Ashley Karpinos, MD, MPH, and research partners surveyed members of tennis and golf teams in five National Collegiate Athletic Association Division I conferences. Spending up to four hours per… Read More

According to a recent study released in Pediatrics, youth who suffer nonfatal firearm injuries have a significantly increased risk of hospitalizations, emergency department (ED) visits, outpatient visits and costs in the 12 months following injury compared to youth without a firearm injury. “We’ve seen firearm injuries in youth dramatically climb over… Read More

Developing and evaluating pediatric phecodes (Peds-Phecodes) for high-throughput phenotyping using electronic health records. Grabowska ME, Van Driest SL, Robinson JR, Patrick AE, Guardo C, Gangireddy S, Ong HH, Feng Q, Carroll R, Kannankeril PJ, Wei WQ. J Am Med… Read More

Vanderbilt University Medical Center has received a $10 million, five-year research funding award from the Patient-Centered Outcomes Research Institute (PCORI) to study the ideal “dose” of behavioral interventions to treat childhood obesity in rural and minority communities across Tennessee and Louisiana. Bill Heerman, MD, MPH, chief of the Division of… Read More

Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of raptor and this contributes to the weight loss effect of liraglutide. Le TDV, Liu D, Besing GK, Raghavan R, Ellis BJ, Ceddia RP, Collins S, Ayala JE. Elife. 2023 Nov 6;12:e80944. Read More

If you sequence the DNA of adult research participants with respect to pathologic variants that, if found, could be expected to prompt diagnostic tests and perhaps also preventive measures, and you return that information to participants and their doctors along with preventive care recommendations, many of those found at risk… Read More

COVID-19 cases in the United States, first reported on January 22, 2020, began to increase in March 2020 (1). The pandemic resulted in a substantial number of employed persons being laid off or furloughed, especially during spring 2020, and increased prevalence of teleworking (2–4). Employers were advised to actively encourage… Read More

Neuropsychiatric complications among children and adolescents with influenza are poorly studied and often attributed to antiviral medication, or a combination of antivirals and influenza. But a better understanding these events and their causes is important for determining risk stratification and prevention strategies, according to Vanderbilt University Medical… Read More